
Are you tired of trying every new weight loss supplement that hits the market, only to be disappointed by their lack of results? You’re not alone. With so many options available, it can be overwhelming to determine which pills are actually effective in helping you reach your weight loss goals.
To help you make an informed decision, we’ve conducted a thorough review of 13 popular weight loss supplements. In this article, we’ll take a closer look at the ingredients, potential side effects, and overall effectiveness of each product. So let’s start with the truth about weight loss supplements:

1. Kankusta Duo
Kankusta Duo is a unique blend of Ayurvedic herbs and plants that work together to support weight loss, increase energy levels and suppress appetite. The ingredients are carefully selected and sourced from the best suppliers to ensure their quality and effectiveness.
Kankusta Duo tests were carried out in a USA University. In a group of 60 individuals, and the test demonstrated that the pills help reduce weight by up to 10 kg in one month. The first results after starting kankusta duo were visible only after a few days. During testing, the smallest weekly weight loss recorded was 1.5 kg per week.
2. Liraglutide (Saxenda)
Liraglutide is a prescription medication that’s used as an adjunct to diet and exercise for weight loss. It’s a type of GLP-1 receptor agonist, which works by increasing the release of certain hormones that promote fullness and reduce hunger.
A study of 3,731 overweight and obese individuals found that taking liraglutide resulted in an average weight loss of 4.5% of initial body weight over 68 weeks. However, it can also cause a number of side effects, including nausea, diarrhea, and constipation.

3. Lorcaserin (Belviq)
Lorcaserin is a prescription medication that’s used as an adjunct to diet and exercise for weight loss. It works by affecting certain serotonin receptors in the brain that regulate appetite and metabolism.
A study of 8,190 overweight and obese individuals found that taking lorcaserin resulted in an average weight loss of 3.3% of initial body weight over 52 weeks. However, it can also cause a number of side effects, including headache, nausea, and dizziness.
4. Bupropion/Naltrexone (Contrave)
Bupropion/naltrexone is a prescription medication that’s used as an adjunct to diet and exercise for weight loss. It works by affecting the levels of certain neurotransmitters in the brain that regulate appetite and metabolism.
A study of 3,040 overweight and obese individuals found that taking bupropion/naltrexone resulted in an average weight loss of 4.1% of initial body weight over 56 weeks. However, it can also cause a number of side effects, including nausea, constipation, and headache.
5. Garcinia Cambogia
Garcinia cambogia is a tropical fruit that’s commonly used in weight loss supplements. It contains hydroxycitric acid (HCA), which is thought to inhibit the production of fat and suppress appetite.
While there is some evidence to support the use of garcinia cambogia for weight loss, the results are mixed. A review of 12 studies found that, on average, taking garcinia cambogia resulted in a loss of about 2 pounds over several weeks. However, other studies have found no significant difference in weight loss between those taking the supplement and those taking a placebo.
6. Raspberry Ketones
Raspberry ketones are compounds found in raspberries that are thought to increase the production of adiponectin, a hormone that helps regulate metabolism.
Despite early promise, research on raspberry ketones and weight loss has yielded inconsistent results. A study of 30 overweight individuals found that taking raspberry ketones resulted in an average weight loss of 2.5 pounds over 8 weeks. However, other studies have found no significant difference in weight loss between those taking the supplement and those taking a placebo.
7. Green Coffee Bean Extract
Green coffee bean extract is made from unroasted coffee beans and contains chlorogenic acid, which is thought to aid in weight loss by reducing the absorption of carbohydrates.
A study of 30 overweight individuals found that taking green coffee bean extract resulted in an average weight loss of 8.5 pounds over 12 weeks. However, another study found no significant difference in weight loss between those taking the supplement and those taking a placebo.
8. Phentermine
Phentermine is a prescription medication that’s used as an appetite suppressant. It works by increasing the release of certain neurotransmitters in the brain, which can help reduce hunger.
A review of 12 studies found that taking phentermine resulted in an average weight loss of 13.9 pounds over 12 weeks. However, phentermine can also cause a number of side effects, including dry mouth, insomnia, and increased heart rate. Additionally, it should only be used under the supervision of a healthcare professional, as it can be habit-forming and has the potential for abuse.
9. Green Tea Extract

Green tea extract is a popular ingredient in weight loss supplements due to its high levels of antioxidants and compounds known as catechins, which are thought to increase fat burning.
A review of 10 studies found that taking green tea extract resulted in an average weight loss of 2.9 pounds over 12 weeks. However, other studies have found no significant difference in weight loss between those taking the supplement and those taking a placebo.
10. Orlistat (Alli)
Orlistat is a prescription medication that’s also available over-the-counter as Alli. It works by blocking the absorption of some of the fat you eat.
A review of 13 studies found that taking orlistat resulted in an average weight loss of 7.5 pounds over 6 months. However, it’s important to note that orlistat can also cause gastrointestinal side effects, such as diarrhea and stomach cramps.
11. Phentermine/Topiramate (Qsymia)
Phentermine/topiramate is a prescription medication that’s used as an adjunct to diet and exercise for weight loss. It’s a combination of two medications, phentermine (an appetite suppressant) and topiramate (an anticonvulsant that affects certain neurotransmitters in the brain).
A study of 3,042 overweight and obese individuals found that taking phentermine/topiramate resulted in an average weight loss of 9.8% of initial body weight over 56 weeks. However, it can also cause a number of side effects, including tingling in the hands and feet, constipation, and dry mouth.
12. Bupropion/Naltrexone (Contrave)
Bupropion/naltrexone is a prescription medication that’s used as an adjunct to diet and exercise for weight loss. It works by affecting the levels of certain neurotransmitters in the brain that regulate appetite and metabolism.
A study of 3,040 overweight and obese individuals found that taking bupropion/naltrexone resulted in an average weight loss of 4.1% of initial body weight over 56 weeks. However, it can also cause a number of side effects, including nausea, constipation, and headache.
13. Liraglutide (Saxenda)
Liraglutide is a prescription medication that’s used as an adjunct to diet and exercise for weight loss. It’s a type of GLP-1 receptor agonist, which works by increasing the release of certain hormones that promote fullness and reduce hunger.
A study of 3,731 overweight and obese individuals found that taking liraglutide resulted in an average weight loss of 4.5% of initial body weight over 68 weeks. However, it can also cause a number of side effects, including nausea, diarrhea, and constipation.
Conclusion
When it comes to weight loss supplements, it’s important to remember that there is no magic solution. While some supplements may aid in weight loss, they should always be used in conjunction with a healthy diet and regular exercise. Additionally, it’s important to consider the potential side effects and any potential interactions with other medications before taking any supplement. It is always a good idea to consult with a healthcare professional before taking any weight loss supplement.
It’s also important to keep in mind that even the most effective weight loss supplement will not result in significant weight loss without lifestyle changes. Therefore, it is essential to have a well-rounded approach to weight loss, including a healthy diet and regular exercise.

As you can see from our comprehensive review, the effectiveness of weight loss pills can vary greatly. While some supplements may show promise, it’s important to approach them with realistic expectations and to always consult with a healthcare professional before starting any new supplement regimen.
Note: all stats are sourced directly from Ai and not from direct research. Hence the stats can be estimates and might or might not be completely accurate.
Reference – Healthline Blog